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elderly patient

Practice targeted AMC-style multiple-choice questions on elderly patient.

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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 72-year-old female presents with right leg pain and skin changes after starting warfarin for atrial fibrillation. Her INR is 3.5. Examination reveals the findings in the image. What is the MOST appropriate next step in management?

A. Administer vitamin K and discontinue warfarin
B. Elevate the leg and apply compression bandages
C. Prescribe a broad-spectrum antibiotic
D. Apply topical corticosteroids
E. Increase the dose of warfarin
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 72-year-old woman with a history of well-controlled hypertension presents with sudden-onset headache and vomiting. Neurological exam reveals mild neck stiffness but is otherwise normal. A CT angiogram reveals a posterior communicating artery aneurysm, which was subsequently coiled. The image shows a post-coiling angiogram. 24 hours post-procedure, she develops worsening headache and new-onset right-sided weakness. What is the MOST appropriate next step?

A. Start aspirin and clopidogrel
B. Increase the dose of her antihypertensive medication
C. Perform lumbar puncture
D. Repeat CT angiogram
E. Administer nimodipine
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A 65-year-old man with a Popeye deformity has persistent pain and weakness despite conservative management. What is the next step?

A. Refer for surgical repair.
B. Observe for 6 months.
C. Order an MRI.
D. Start physical therapy.
E. Prescribe NSAIDs.
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An old man presents with 6 months of memory decline, falls, visual hallucinations, agitation, and confusion. Which of the following features is relevant to diagnosing his condition?

A. Parkinsonian features
B. Normal CSF markers for amyloid and tau.
C. Cerebellar signs
D. Significant early memory impairment.
E. Absence of motor symptoms.
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A 67-year-old man with a history of hypertension and type 2 diabetes is scheduled for elective cholecystectomy due to symptomatic gallstones. During the preoperative assessment, he mentions experiencing mild chest discomfort during exertion over the past few weeks. What is the most appropriate next step in his preoperative management?

A. Start the patient on aspirin and beta-blockers immediately
B. Order a preoperative chest X-ray
C. Refer for a cardiology evaluation and possible stress testing
D. Proceed with surgery as planned with close intraoperative monitoring
E. Schedule an urgent coronary angiogram
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old male presents to his general practitioner complaining of mild, chronic lower back pain that has been present for several months. He describes the pain as a dull ache, worse with prolonged standing. He has a significant past medical history including hypertension, hyperlipidemia, and a 50-pack-year smoking history, all of which are currently managed with medications. He denies any acute abdominal pain, pulsatile sensation, or leg symptoms. On physical examination, his vital signs are stable: blood pressure 135/85 mmHg, heart rate 72 bpm, respiratory rate 14 breaths/min, and oxygen saturation 99% on room air. Abdominal examination is soft, non-tender, with no palpable masses. Peripheral pulses are symmetric and strong. As part of the investigation into his chronic back pain, a contrast-enhanced CT scan of the abdomen and pelvis is performed. An axial view from the scan is shown. Based on the clinical presentation and the findings demonstrated in the provided image, which of the following is the MOST appropriate next step in management?

A. Refer urgently to a vascular surgeon for consideration of immediate endovascular repair.
B. Initiate a program of regular surveillance imaging with ultrasound and aggressively manage cardiovascular risk factors.
C. Reassure the patient that the finding is incidental and benign, and focus solely on managing his chronic back pain.
D. Arrange for immediate admission to hospital for observation and further investigation.
E. Schedule a repeat CT scan with contrast within 3 months to assess for rapid expansion.
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 72-year-old male presents with increasing dyspnea. He has a history of GORD. The provided image was taken. What is the most appropriate next step?

A. Refer for surgical consultation for fundoplication.
B. Prescribe prokinetic agents to improve gastric emptying.
C. Initiate a trial of PPI therapy and lifestyle modifications.
D. Order a barium swallow study to further evaluate the anatomy.
E. Perform an upper endoscopy to assess for complications.
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the emergency department with a 12-hour history of severe, constant left groin pain. He reports a bulge in his groin that has been present for several years, which he can usually reduce himself. However, today he has been unable to push it back in, and the pain has become excruciating. He denies any fever, nausea, or vomiting. On examination, his vital signs are stable: temperature 37.0°C, heart rate 88 bpm, blood pressure 130/80 mmHg, respiratory rate 16 breaths/min, and oxygen saturation 98% on room air. Abdominal examination is unremarkable. Palpation of the left groin reveals a firm, tender mass that is non-reducible. The overlying skin is erythematous, but there is no crepitus. A CT scan of the abdomen and pelvis is performed, and an axial slice is shown. Given the clinical scenario and the imaging findings, what is the MOST appropriate next step in management?

A. Order a repeat CT scan with intravenous contrast in 6 hours to assess for bowel ischemia
B. Prescribe oral analgesics and instruct the patient to follow up with his general practitioner in 24 hours
C. Surgical consultation for emergent operative intervention
D. Attempt manual reduction with intravenous sedation and analgesia
E. Administer broad-spectrum antibiotics and observe for improvement
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old woman with a history of hypertension presents with a severe headache and altered mental status. Aneurysm coiling was performed. The image shows a post-operative angiogram. 6 hours later, she develops a fever of 38.5°C and worsening neurological deficits. What is the MOST likely cause?

A. Meningitis
B. Coil migration
C. Hemorrhagic conversion
D. Hydrocephalus
E. Vasospasm
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A 75-year-old obese man with a history of hypertension and chronic lower limb skin changes, swelling, tingling, and weakness presents with sudden onset inability to stand or move his legs, accompanied by a loss of sensation extending up to his waist. On examination, he has flaccid paralysis of both lower limbs, absent deep tendon reflexes in the legs, and a sensory level at the umbilicus. Which of the following is the most appropriate initial investigation?

A. Urgent MRI of the spine
B. Electromyography and nerve conduction studies
C. CT angiography of the aorta and iliac arteries
D. Lumbar puncture
E. Urgent CT scan of the spine
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 75-year-old male with a history of atrial fibrillation on warfarin presents to the emergency department with acute onset shortness of breath and right-sided chest pain. His vital signs are stable. His INR is found to be 7.2. A chest CT is performed (image attached). Based on the clinical presentation and imaging findings, what is the MOST appropriate immediate management step?

A. Administer Vitamin K and Prothrombinex (PCC) and prepare for chest tube insertion.
B. Administer Fresh Frozen Plasma (FFP) and arrange for surgical consultation.
C. Prescribe analgesia and observe the patient for clinical improvement.
D. Proceed directly to chest tube insertion without reversing anticoagulation.
E. Administer Vitamin K only and monitor the patient closely.
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A 68-year-old male with a history of hypertension and stable angina is prescribed amlodipine. He returns after two weeks complaining of significant ankle edema. What is the most appropriate initial management step?

A. Add a beta-blocker to counteract the effects of amlodipine.
B. Advise the patient to elevate his legs and wear compression stockings.
C. Reduce the dose of amlodipine.
D. Switch to an alternative antihypertensive such as an ACE inhibitor or ARB.
E. Prescribe a diuretic to manage the edema.
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 72-year-old woman presents with a long history of heartburn, regurgitation, and recently developed a chronic cough, particularly at night. Physical examination is unremarkable. A chest radiograph is obtained. Considering the radiographic findings in the context of the patient's presentation, what is the most likely pathophysiological mechanism contributing to her chronic cough?

A. Pulmonary oedema secondary to cardiac dysfunction
B. Interstitial lung disease causing restrictive ventilatory defect
C. Compression of the left main bronchus by an enlarged lymph node
D. Bronchial hyperreactivity triggered by inhaled allergens
E. Chronic aspiration of gastric contents
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 65-year-old male with known alcoholic cirrhosis presents for routine HCC screening. His AFP is 25 ng/mL. A CT scan with IV contrast is performed (image attached). What is the MOST appropriate next step in management?

A. MRI of the abdomen with contrast
B. Repeat AFP in 3 months
C. Initiate sorafenib
D. Surgical resection
E. Referral for liver transplant evaluation
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 68-year-old woman presents to her GP with a 3-month history of a persistent, mildly pruritic skin lesion on her left chest wall. She had a left simple mastectomy for invasive ductal carcinoma 10 years ago, followed by adjuvant therapy. She denies fever, weight loss, or other systemic symptoms. Physical examination reveals the appearance shown. What is the most appropriate initial diagnostic investigation?

A. Prescribe a course of topical antifungal cream
B. Punch biopsy of the lesion
C. Order a PET-CT scan for staging
D. Arrange a follow-up appointment in 3 months to monitor the lesion
E. Perform a shave biopsy of the lesion
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A 65-year-old man undergoes successful coil embolization of a ruptured anterior communicating artery aneurysm. Two days post-procedure, he develops a temperature of 38.1°C, generalized malaise, and a headache unresponsive to paracetamol. Neurological exam is unchanged from baseline. CRP is 45 mg/L (normal <5). Which of the following is the most likely cause of his current symptoms?

A. Bacterial meningitis
B. Post-embolization syndrome
C. Re-rupture of the aneurysm
D. Vasospasm
E. Deep vein thrombosis
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CT, ultrasonography, SPECT and scintigraphy of intra-thyroid parathyroid adenoma
Image by Mnahi Bin Saeedan, Ibtisam Musallam Aljohani, Ayman Omar Khushaim, Salwa Qasim Bukhari, Salahudin Tayeb Elnaas CC BY 4.0 · Source

A 62-year-old woman with osteoporosis and a history of kidney stones presents with a serum calcium of 2.9 mmol/L (2.1-2.6 mmol/L) and PTH of 120 pg/mL (10-65 pg/mL). She denies neck pain or swelling. The provided imaging was obtained. What is the MOST appropriate next step?

A. Cinacalcet to lower PTH levels
B. Vitamin D and calcium supplementation
C. Surgical excision of the identified lesion
D. Bisphosphonate therapy and observation
E. Thyroidectomy
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman with past colicky pain has the ultrasound shown. LFTs are normal. What is the MOST appropriate next investigation?

A. Hepatobiliary Iminodiacetic Acid (HIDA) scan
B. Endoscopic ultrasound (EUS)
C. MRCP
D. Repeat ultrasound in 3 months
E. CT Abdomen
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A 68-year-old man with a history of poorly controlled type 2 diabetes, hypertension, and chronic kidney disease (stage 3) presents to the emergency department with severe abdominal pain and vomiting. On examination, he has a distended abdomen with diffuse tenderness and guarding. His vital signs show a blood pressure of 90/60 mmHg, heart rate of 110 bpm, and a temperature of 38.5°C. Laboratory tests reveal leukocytosis, elevated serum lactate, and worsening renal function. A CT scan of the abdomen shows pneumoperitoneum and free fluid, suggesting perforated viscus. What is the most appropriate next step in the management of this patient?

A. Immediate exploratory laparotomy
B. Administer intravenous fluids and reassess in 2 hours
C. Initiate broad-spectrum antibiotics and observe
D. Consult nephrology for dialysis before surgery
E. Perform a diagnostic laparoscopy
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A 62-year-old female has high blood pressure (162/97 mmHg) but is not concerned. She has white coat hypertension and declines 24-hour BP monitoring. What is the correct instruction about home blood pressure readings?

A. Check blood pressure immediately after waking up.
B. Check BP before daily medications.
C. Check blood pressure while talking or watching TV.
D. Check blood pressure only when feeling unwell.
E. Check blood pressure after food and exercise.
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents with a 2-day history of worsening left lower quadrant abdominal pain, fever (38.5°C), and nausea. He has a history of similar, milder pain episodes. Examination reveals left iliac fossa tenderness with guarding. Bloods show WCC 16, CRP 120. A CT scan is performed (image provided). Considering the clinical picture and the imaging findings, which of the following represents the most appropriate initial management strategy?

A. Administer intravenous fluids and analgesia, and observe in the emergency department for 12 hours.
B. Initiate intravenous broad-spectrum antibiotics and admit for inpatient care.
C. Arrange urgent surgical review for consideration of immediate operative intervention.
D. Prescribe oral antibiotics and arrange follow-up with his general practitioner.
E. Schedule an urgent colonoscopy to evaluate the severity and rule out malignancy.
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A 70-year-old male presents to the emergency department with severe abdominal and back pain. He has a history of hypertension and smoking. On examination, he is hypotensive and tachycardic. Palpation reveals a pulsatile abdominal mass. What is the most likely diagnosis?

A. Ruptured abdominal aortic aneurysm
B. Renal colic
C. Acute pancreatitis
D. Myocardial infarction
E. Diverticulitis
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old presents with worsening headaches post-aneurysm coiling. The image shows a follow-up angiogram. What is the MOST appropriate next step?

A. Conservative management with analgesia
B. Initiate nimodipine
C. Repeat coiling
D. Start warfarin
E. Prescribe aspirin
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

A 62-year-old woman presents for her routine screening mammogram. She reports no breast symptoms, and physical examination is unremarkable. Her medical history includes well-controlled type 2 diabetes and hyperlipidaemia. She has no family history of breast cancer. The provided image is a magnified view from the craniocaudal projection of the right breast. Considering the clinical context and the findings demonstrated, what is the most appropriate immediate next step in the management of this patient?

A. Breast ultrasound of the area
B. Referral to a medical oncologist for systemic therapy planning
C. Repeat screening mammogram in 6 months
D. Stereotactic core needle biopsy of the area
E. Excisional biopsy under wire localisation
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A 62-year-old woman presents with tiredness and is found to have B12 deficiency. What is the likely associated condition?

A. Pernicious anemia
B. Recent viral infection
C. Sulphonylurea use
D. Low vegetable, high meat diet.
E. Iron deficiency anemia
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 65-year-old man with chronic hepatitis C and compensated cirrhosis (Child-Pugh A) presents for routine surveillance. His alpha-fetoprotein is 250 ng/mL. He feels well. The provided images are obtained. Considering the clinical context and the findings demonstrated in the images, which of the following management strategies is most likely to be the initial approach for this patient?

A. Liver transplantation
B. Radiofrequency ablation (RFA)
C. Palliative care
D. Systemic chemotherapy
E. Transarterial chemoembolisation (TACE)
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 72-year-old woman presents with a 3-month history of worsening constipation, occasional bright red rectal bleeding, and unintentional weight loss of 4 kg. She reports feeling increasingly tired. Her past medical history includes hypertension and osteoarthritis. On examination, her vital signs are stable. Abdominal examination is soft, non-tender, with no palpable masses. Digital rectal examination reveals no palpable lesion. Blood tests show a haemoglobin of 108 g/L, MCV 78 fL, and ferritin 12 µg/L. A colonoscopy was performed, and the image provided was captured during the procedure. Considering the clinical presentation and the finding observed during the colonoscopy, which of the following investigations is most crucial for determining the extent of disease and guiding definitive treatment planning within the multidisciplinary team framework?

A. Repeat colonoscopy in 3 months
B. Commencement of iron supplementation and review in 4 weeks
C. Urgent surgical consultation for immediate resection
D. CT scan of chest, abdomen, and pelvis
E. Referral for palliative care assessment
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 65-year-old patient with a history of smoking presents with a chronic cough and mild weight loss over three months. Physical examination is unremarkable, and vital signs are stable. Routine blood tests, including full blood count and inflammatory markers, are within normal limits. A chest X-ray revealed a solitary pulmonary nodule in the right upper lobe. Subsequent PET-CT imaging was performed as part of the diagnostic workup. Considering the findings demonstrated in the image provided in the context of this patient's presentation, which of the following is the most appropriate next step in the management of this patient?

A. Refer for surgical consultation for lobectomy
B. Obtain tissue diagnosis via biopsy
C. Initiate empirical anti-tuberculosis therapy
D. Schedule follow-up CT scan in three months
E. Perform sputum microscopy and culture for acid-fast bacilli
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old man presents with sudden onset of severe right groin pain and a firm, non-reducible bulge. He reports mild nausea but denies vomiting or change in bowel habit. Vital signs are stable. A CT scan of the pelvis is performed, as shown. Considering the clinical context and the imaging findings, what is the most appropriate immediate management?

A. Obtain a groin ultrasound for further assessment
B. Attempt manual reduction under sedation
C. Arrange for elective surgical consultation
D. Administer analgesia and observe closely
E. Emergency surgical exploration and repair
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman presents for an elective abdominal ultrasound. Several months ago, she experienced a few episodes of intermittent, moderate-to-severe right upper quadrant pain that resolved spontaneously within a few hours each time. She denies any associated fever, chills, nausea, vomiting, or jaundice during those episodes or currently. She has no significant past medical history other than well-controlled hypertension. On examination today, she is afebrile, her vital signs are stable, and her abdomen is soft and non-tender. Routine blood tests performed prior to the ultrasound, including full blood count, liver function tests (bilirubin, alkaline phosphatase, AST, ALT, GGT), amylase, and lipase, are all within their respective normal reference ranges. The provided image is a representative view obtained during her ultrasound examination. Considering the patient's history, current clinical status, and the findings demonstrated in the image, what is the most appropriate next step in the management of this patient?

A. Advise watchful waiting and review if symptoms recur.
B. Schedule elective Endoscopic Retrograde Cholangiopancreatography (ERCP) for stone extraction.
C. Proceed directly to laparoscopic cholecystectomy.
D. Prescribe ursodeoxycholic acid to dissolve the stone.
E. Arrange Magnetic Resonance Cholangiopancreatography (MRCP) to further evaluate the biliary tree.
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 68-year-old male with a history of chronic hepatitis C presents to the clinic complaining of right upper quadrant abdominal pain and unintentional weight loss of 10 kg over the past 6 months. His past medical history is significant for well-controlled hypertension and hyperlipidemia. Physical examination reveals mild hepatomegaly. Laboratory investigations show elevated alpha-fetoprotein (AFP) levels. A contrast-enhanced ultrasound of the liver is performed, and representative images are shown. Based on the imaging and clinical context, which of the following is the MOST appropriate next step in management?

A. Radiofrequency ablation of the lesion
B. Surveillance with serial AFP measurements and ultrasound every 3 months
C. Surgical resection of the lesion
D. Initiation of systemic chemotherapy with sorafenib
E. Referral for liver biopsy to confirm diagnosis and assess grade
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 68-year-old presents with a 3-day history of fever, jaundice, and severe RUQ pain radiating to the back. Vitals: T 38.5°C, BP 110/70, HR 95. LFTs show bilirubin 150, ALP 450, ALT 120. An ERCP is performed for stone extraction. The image is captured during the procedure after cannulation. Considering the findings demonstrated in the image, what is the most appropriate immediate next step in management during the current procedure?

A. Attempt balloon dilation of the distal duct without sphincterotomy
B. Place a biliary stent and schedule follow-up ERCP
C. Perform endoscopic sphincterotomy
D. Attempt stone fragmentation with lithotripsy before sphincterotomy
E. Abandon the procedure and refer for surgical exploration
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A 67-year-old woman presents to her GP with fatigue, weight loss, and night sweats over the past two months. She has a history of smoking and hypertension. On examination, she has palpable lymphadenopathy in the cervical and axillary regions. Blood tests reveal a hemoglobin level of 10 g/dL, elevated lactate dehydrogenase (LDH), and a peripheral blood smear showing atypical lymphocytes. What is the most likely diagnosis?

A. Non-Hodgkin's lymphoma
B. Multiple myeloma
C. Hodgkin's lymphoma
D. Chronic lymphocytic leukemia (CLL)
E. Acute myeloid leukemia (AML)
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 65-year-old male with Hepatitis C cirrhosis is undergoing routine surveillance. A liver lesion was identified on initial ultrasound, prompting a contrast-enhanced ultrasound study. Considering the findings demonstrated in the provided images, what is the most appropriate next step in the management of this patient?

A. Repeat ultrasound in 3 months
B. Refer for urgent liver transplant assessment
C. Prescribe antibiotics for suspected abscess
D. Liver biopsy for histological confirmation
E. Initiate palliative care
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

An 82-year-old patient presents with a 6-month history of chronic cough, intermittent dyspnea, and occasional regurgitation, particularly when lying flat. They deny significant chest pain or weight loss. Past medical history includes well-controlled hypertension and mild asthma managed with salbutamol PRN. On examination, vital signs are stable, and lung sounds are clear with no wheeze. An outpatient chest X-ray was performed as part of the workup for the cough and dyspnea. Considering the radiographic findings in conjunction with the clinical history, which of the following investigations is most appropriate at this stage?

A. High-resolution CT chest
B. Oesophago-gastro-duodenoscopy (OGD)
C. Pulmonary function tests
D. 24-hour oesophageal pH monitoring
E. Cardiac stress test
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A 70-80 year old lady being treated for pulmonary embolism with a therapeutic dose of subcutaneous Enoxaparin is found to have multiple new pulmonary emboli. What is the most appropriate next step?

A. Start streptokinase infusion.
B. Switch to intravenous unfractionated heparin.
C. Switch to oral warfarin.
D. Increase the dose of subcutaneous enoxaparin.
E. Insert an IVC filter.
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 72-year-old woman presents with iron deficiency anaemia and a 4-month history of intermittent lower abdominal pain and tenesmus. Colonoscopy was performed, and the image shows a finding in the sigmoid colon. Biopsies are pending but highly suspicious for malignancy. What is the MOST appropriate initial staging investigation?

A. CT scan of chest, abdomen, and pelvis
B. Endoscopic ultrasound
C. PET scan
D. MRI pelvis
E. Bone scan
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 68-year-old woman presents to her general practitioner with a persistent, pruritic rash on her chest wall. She reports a history of left mastectomy for invasive ductal carcinoma 8 years ago, followed by adjuvant chemotherapy and radiation therapy. She denies any recent trauma or changes in soaps or detergents. Physical examination reveals the findings shown. A punch biopsy is performed. Which of the following immunohistochemical stains would most likely be positive in this patient's biopsy sample, supporting the suspected diagnosis?

A. Vimentin
B. Cytokeratin 7 (CK7)
C. Smooth muscle actin (SMA)
D. S-100
E. Human epidermal growth factor receptor 2 (HER2)
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 68-year-old presents with a 3-day history of fever, jaundice, and severe RUQ pain radiating to the back. Vitals: T 38.5°C, BP 110/70, HR 95. LFTs show bilirubin 150, ALP 450, ALT 120. An ERCP is performed for stone extraction. The image is captured during the procedure after cannulation. Considering the findings demonstrated in the image, what is the most appropriate immediate next step in management during the current procedure?

A. Proceed with mechanical lithotripsy after sphincterotomy.
B. Place a biliary stent for decompression.
C. Attempt extraction with a balloon catheter after sphincterotomy.
D. Refer for urgent laparoscopic common bile duct exploration.
E. Terminate the procedure and manage medically.
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

An 82-year-old patient presents to the emergency department with a 3-month history of intermittent retrosternal chest discomfort, worse after meals, and mild shortness of breath on exertion. They report occasional regurgitation but deny significant dysphagia. Past medical history includes hypertension and osteoarthritis. Medications are perindopril and paracetamol. On examination, vital signs are stable, and lung sounds are clear. A chest X-ray is performed. Based on the findings in the image, what is the most appropriate next step in management or investigation?

A. Arrange for an Oesophago-Gastro-Duodenoscopy (OGD)
B. Order a CT pulmonary angiogram
C. Advise on weight loss and elevate the head of the bed
D. Initiate treatment with a high-dose proton pump inhibitor
E. Perform a stress echocardiogram
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 72-year-old woman presents with a persistent, slowly expanding skin lesion on her right chest wall, present for several months. She underwent a right mastectomy for invasive ductal carcinoma 12 years ago. She denies pain, discharge, or systemic symptoms. Physical examination reveals the appearance shown. Considering the patient's history and the clinical finding, which of the following investigations is most appropriate to assess for potential underlying malignancy or systemic involvement?

A. Bone scan
B. Serum tumour markers (CA 15-3, CEA)
C. Mammography of the contralateral breast
D. CT scan of chest, abdomen, and pelvis
E. PET scan
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A 72-year-old man with a history of hypertension and type 2 diabetes mellitus is being managed with lisinopril. He presents to the emergency department complaining of lip swelling and difficulty breathing. On examination, his tongue appears swollen. What is the most appropriate immediate management?

A. Administer intramuscular epinephrine
B. Administer intravenous corticosteroids
C. Administer nebulized bronchodilators
D. Administer intravenous antihistamines
E. Observe and monitor vital signs
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 72-year-old male presents with a 4-month history of increasing constipation and occasional streaks of blood on stool. He denies significant weight loss. Physical exam is unremarkable. A colonoscopy was performed, and the image is shown. Biopsies are taken from the lesion. Assuming the biopsy confirms adenocarcinoma, what is the MOST appropriate initial investigation to guide further management?

A. Referral for neoadjuvant chemotherapy
B. CT scan of chest, abdomen, and pelvis
C. Repeat colonoscopy in 3 months
D. PET scan for distant metastases
E. Endoscopic ultrasound for local staging
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A 65-year-old man presents to the emergency department with sudden onset of severe headache, nausea, and vomiting. He has a history of hypertension and is currently on antihypertensive medication. On examination, he is alert but in distress due to the headache. His blood pressure is 180/110 mmHg, heart rate is 90 bpm, and he has no focal neurological deficits. A CT scan of the head shows a subarachnoid hemorrhage. Which of the following is the most appropriate initial management step in this patient?

A. Administer nimodipine to prevent cerebral vasospasm
B. Perform immediate surgical clipping of the aneurysm
C. Administer mannitol to reduce intracranial pressure
D. Start intravenous labetalol to control blood pressure
E. Initiate anticonvulsant therapy to prevent seizures
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old male undergoes a CT scan for investigation of chronic back pain. He denies abdominal pain or pulsatile mass. His blood pressure is 130/80 mmHg. The provided image is an axial view from this scan. Based on this finding and the patient's clinical status, what is the most appropriate next step in management according to Australian guidelines?

A. Arrange for surveillance ultrasound in 12 months
B. Repeat CT angiography in 6 months
C. Arrange for urgent surgical consultation
D. No further follow-up is required
E. Schedule elective endovascular aneurysm repair (EVAR)
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A 68-year-old man with a history of smoking and hypertension presents with intermittent claudication in his right leg. Ankle-brachial index (ABI) is 0.6 on the right and 0.9 on the left. He has been on a supervised exercise program and optimal medical therapy for 6 months with no improvement in symptoms. What is the most appropriate next step in management?

A. Continue with the current exercise program and medical therapy
B. Consideration for revascularization with angioplasty or bypass surgery
C. Start a trial of cilostazol
D. Increase the dose of his antihypertensive medication
E. Refer for a vascular ultrasound to reassess the ABI
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 68-year-old woman presents to the emergency department with right upper quadrant abdominal pain, fever, and jaundice. Her past medical history is significant for hypertension and hyperlipidemia. Initial laboratory investigations reveal elevated bilirubin, alkaline phosphatase, and gamma-glutamyl transferase (GGT) levels. An ultrasound of the abdomen showed dilated intrahepatic ducts, but the common bile duct was difficult to visualize due to overlying bowel gas. An ERCP was performed, and an image obtained during the procedure is shown. Following successful removal of the obstruction, what is the MOST appropriate next step in managing this patient's condition?

A. Prescribe oral ursodeoxycholic acid
B. Schedule a laparoscopic cholecystectomy
C. Administer intravenous antibiotics and monitor liver function tests
D. Perform a percutaneous transhepatic cholangiogram
E. Discharge the patient with instructions for a low-fat diet
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 72-year-old woman on warfarin for chronic atrial fibrillation presents with a painful, rapidly expanding lesion on her right lower leg that began two days ago, shortly after her warfarin dose was increased. Her vital signs are stable, and her INR is within the therapeutic range. Considering the clinical presentation and the appearance of the lesion shown, what is the most appropriate immediate management?

A. Administer broad-spectrum antibiotics and arrange urgent surgical debridement.
B. Switch warfarin to a direct oral anticoagulant (DOAC).
C. Discontinue warfarin, administer vitamin K, and initiate heparin.
D. Continue warfarin at the current dose and monitor closely.
E. Reduce the warfarin dose and add aspirin.
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 78-year-old male on warfarin presents with acute shortness of breath. INR is 5.0. The provided image was obtained. What is the MOST likely underlying cause?

A. Pneumonia
B. Anticoagulation-related bleeding
C. Heart failure exacerbation
D. Pulmonary embolism
E. Spontaneous pneumothorax
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 68-year-old male presents with fatigue, weight loss, and vague abdominal discomfort. His past medical history includes a recent diagnosis of gastric mixed adenoneuroendocrine carcinoma (MANEC). A CT scan of the abdomen is performed, as shown. Which of the following is the MOST appropriate next step in management?

A. Initiation of immunotherapy
B. Palliative chemotherapy
C. Observation with serial imaging
D. Transarterial chemoembolization (TACE)
E. Surgical resection of the liver lesions
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