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elderly patient

Practice targeted AMC-style multiple-choice questions on elderly patient.

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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents with abdominal distension, obstipation, and vomiting. He has a history of prior abdominal surgery. An upright abdominal X-ray is performed. What is the MOST appropriate next step in management?

A. Colonoscopy
B. Surgical consultation
C. Barium enema
D. Stool softeners
E. Oral antibiotics
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A 67-year-old man with a history of hypertension and type 2 diabetes is scheduled for elective cholecystectomy due to symptomatic gallstones. During the preoperative assessment, he mentions experiencing mild chest discomfort during exertion over the past few weeks. What is the most appropriate next step in his preoperative management?

A. Start the patient on aspirin and beta-blockers immediately
B. Order a preoperative chest X-ray
C. Refer for a cardiology evaluation and possible stress testing
D. Proceed with surgery as planned with close intraoperative monitoring
E. Schedule an urgent coronary angiogram
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the emergency department with a 12-hour history of severe, constant left groin pain. He reports a bulge in his groin that has been present for several years, which he can usually reduce himself. However, today he has been unable to push it back in, and the pain has become excruciating. He denies any fever, nausea, or vomiting. On examination, his vital signs are stable: temperature 37.0°C, heart rate 88 bpm, blood pressure 130/80 mmHg, respiratory rate 16 breaths/min, and oxygen saturation 98% on room air. Abdominal examination is unremarkable. Palpation of the left groin reveals a firm, tender mass that is non-reducible. The overlying skin is erythematous, but there is no crepitus. A CT scan of the abdomen and pelvis is performed, and an axial slice is shown. Given the clinical scenario and the imaging findings, what is the MOST appropriate next step in management?

A. Order a repeat CT scan with intravenous contrast in 6 hours to assess for bowel ischemia
B. Prescribe oral analgesics and instruct the patient to follow up with his general practitioner in 24 hours
C. Surgical consultation for emergent operative intervention
D. Attempt manual reduction with intravenous sedation and analgesia
E. Administer broad-spectrum antibiotics and observe for improvement
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A 68-year-old woman presents with a 2-week history of progressive weakness in her right arm and leg, associated with a tremor in the right hand. She also reports feeling more tired than usual. Her general practitioner noted an elevated TSH (12 mIU/L, reference range 0.4-4.0 mIU/L) on routine blood tests done a month ago, but free T4 was within the normal range (15 pmol/L, reference range 10-20 pmol/L). On examination, she has mild right-sided hemiparesis (MRC grade 4/5) and a coarse tremor in the right hand, worse with action. Reflexes are brisk on the right. The rest of the neurological exam is unremarkable. She has mild bradycardia (55 bpm) but no other signs of overt hypothyroidism. What is the most appropriate initial investigation?

A. Cerebrospinal fluid analysis
B. Serum anti-thyroid antibodies (e.g., TPO antibodies)
C. CT angiography of the head and neck
D. Repeat thyroid function tests including free T3
E. MRI brain
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the emergency department complaining of new onset left flank pain radiating to his groin. He reports a history of hypertension and hyperlipidemia, both managed with medications. He denies any recent trauma. His vital signs are stable: blood pressure 130/80 mmHg, heart rate 88 bpm, respiratory rate 16 breaths/min, and oxygen saturation 98% on room air. Physical examination reveals mild tenderness to palpation in the left flank, but no guarding or rebound tenderness. Peripheral pulses are normal and symmetric. A contrast-enhanced CT scan of the abdomen and pelvis is performed, the axial view is shown. Given the clinical context and the findings on the image, which of the following is the MOST appropriate next step in management?

A. Referral to vascular surgery for elective repair
B. Order a renal ultrasound to evaluate for hydronephrosis
C. Prescribe analgesics and schedule a repeat CT scan in 6 months
D. Start oral antibiotics for suspected pyelonephritis
E. Initiate intravenous heparin and consult vascular surgery for urgent repair
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CT, ultrasonography, SPECT and scintigraphy of intra-thyroid parathyroid adenoma
Image by Mnahi Bin Saeedan, Ibtisam Musallam Aljohani, Ayman Omar Khushaim, Salwa Qasim Bukhari, Salahudin Tayeb Elnaas CC BY 4.0 · Source

A 62-year-old woman presents with fatigue, bone pain, and constipation. Laboratory tests reveal serum calcium 3.1 mmol/L, PTH 180 pg/mL, and elevated 24-hour urine calcium. Imaging studies are shown. Considering the clinical presentation and investigation findings, what is the MOST appropriate next step in the management of this patient?

A. Further imaging with MRI of the neck
B. Surgical parathyroidectomy
C. Long-term observation with serial calcium and PTH measurements
D. Initiation of medical therapy with cinacalcet
E. Commencement of intravenous bisphosphonate therapy
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 68-year-old woman presents with a persistent rash on her chest wall at the site of a previous mastectomy performed 8 years ago. She denies pain or itching. What is the MOST appropriate next step in management?

A. Reassurance and observation
B. Topical corticosteroid application
C. Skin biopsy
D. Referral to dermatology for cryotherapy
E. Excisional biopsy with wide margins
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 65-year-old woman presents with a chronic, non-healing lesion at the site of her mastectomy scar, performed 7 years ago. She denies pain but reports occasional itching. What is the MOST appropriate next investigation?

A. Mammogram of the contralateral breast
B. Fungal culture
C. Topical corticosteroid application
D. Excisional biopsy with wide margins
E. Skin biopsy
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A 65-year-old man undergoes successful coil embolization of a ruptured anterior communicating artery aneurysm. Two days post-procedure, he develops a temperature of 38.1°C, generalized malaise, and a headache unresponsive to paracetamol. Neurological exam is unchanged from baseline. CRP is 45 mg/L (normal <5). Which of the following is the most likely cause of his current symptoms?

A. Bacterial meningitis
B. Post-embolization syndrome
C. Re-rupture of the aneurysm
D. Vasospasm
E. Deep vein thrombosis
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CT, ultrasonography, SPECT and scintigraphy of intra-thyroid parathyroid adenoma
Image by Mnahi Bin Saeedan, Ibtisam Musallam Aljohani, Ayman Omar Khushaim, Salwa Qasim Bukhari, Salahudin Tayeb Elnaas CC BY 4.0 · Source

A 62-year-old woman presents to her GP with a 6-month history of increasing fatigue, generalised bone aches, and constipation. She denies polyuria or polydipsia. Her past medical history is unremarkable, and she takes no regular medications. On examination, her vital signs are stable, and there are no palpable neck masses. Initial laboratory investigations show serum calcium 3.1 mmol/L (2.1-2.6), phosphate 0.7 mmol/L (0.8-1.4), PTH 180 pg/mL (10-65), and 24-hour urine calcium 450 mg (100-300). She is referred for further imaging, the results of which are shown. Based on the available information, what is the MOST appropriate next step in the management of this patient?

A. Perform a bone mineral density scan
B. Initiate medical therapy with cinacalcet
C. Order genetic testing for MEN syndromes
D. Repeat parathyroid localisation imaging
E. Surgical parathyroidectomy
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 65-year-old male presents to the emergency department with 2 days of constant right upper quadrant pain radiating to the back, associated with nausea and subjective fever. On examination, he is febrile (38.5°C) with significant tenderness and a positive Murphy's sign in the right upper quadrant. His white cell count is elevated at 15 x 10^9/L, and CRP is 120 mg/L. Liver function tests are within normal limits. Considering the clinical findings and the provided imaging, what is the most appropriate next step in the management of this patient?

A. Laparoscopic cholecystectomy within 24-72 hours
B. Urgent endoscopic retrograde cholangiopancreatography (ERCP)
C. Percutaneous cholecystostomy insertion
D. Repeat abdominal CT scan in 24 hours
E. Continue medical management with intravenous antibiotics and analgesia only
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 78-year-old male on warfarin presents to the ED after a fall. He complains of dyspnea and right-sided chest pain. His INR is 5.0. Vitals: HR 110, BP 100/60, RR 28, SpO2 90% on room air. The provided image was obtained. What is the MOST appropriate next step?

A. Administer IV protamine sulfate
B. Tube thoracostomy
C. Administer IV vitamin K
D. Administer IV tranexamic acid
E. Observation with serial chest X-rays
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents with a 2-day history of worsening left lower quadrant abdominal pain, fever (38.5°C), and nausea. He has a history of similar, milder pain episodes. Examination reveals left iliac fossa tenderness with guarding. Bloods show WCC 16, CRP 120. A CT scan is performed (image provided). Considering the clinical picture and the imaging findings, which of the following represents the most appropriate initial management strategy?

A. Administer intravenous fluids and analgesia, and observe in the emergency department for 12 hours.
B. Initiate intravenous broad-spectrum antibiotics and admit for inpatient care.
C. Arrange urgent surgical review for consideration of immediate operative intervention.
D. Prescribe oral antibiotics and arrange follow-up with his general practitioner.
E. Schedule an urgent colonoscopy to evaluate the severity and rule out malignancy.
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CT, ultrasonography, SPECT and scintigraphy of intra-thyroid parathyroid adenoma
Image by Mnahi Bin Saeedan, Ibtisam Musallam Aljohani, Ayman Omar Khushaim, Salwa Qasim Bukhari, Salahudin Tayeb Elnaas CC BY 4.0 · Source

A 62-year-old woman presents to her general practitioner complaining of fatigue, bone pain, and constipation for the past several months. She denies any significant past medical history. Initial laboratory investigations reveal an elevated serum calcium level of 3.1 mmol/L (reference range: 2.1-2.6 mmol/L) and an elevated parathyroid hormone (PTH) level of 180 pg/mL (reference range: 10-65 pg/mL). A 24-hour urine calcium excretion is also elevated. The patient is referred for further imaging, the results of which are shown. Based on the available information, what is the MOST appropriate next step in the management of this patient?

A. Surgical excision of the identified lesion
B. Vitamin D supplementation
C. Cinacalcet administration
D. Initiation of bisphosphonate therapy
E. Observation with serial calcium and PTH monitoring
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 68-year-old male presents with dysphagia and weight loss. Gastroscopy and biopsy confirm gastric adenocarcinoma. Staging CT imaging is shown. His ECOG performance status is 1. Considering the clinical presentation and the findings demonstrated in the provided images, what is the most appropriate initial management strategy for this patient?

A. Proceed with total gastrectomy and D2 lymphadenectomy
B. Refer for liver transplantation assessment
C. Plan palliative radiotherapy to the gastric primary
D. Initiate systemic chemotherapy
E. Consider transarterial chemoembolisation for hepatic lesions
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A 70-year-old man with a history of hypertension and type 2 diabetes mellitus is being treated with an ACE inhibitor. His medications include metformin, gliclazide and perindopril. He presents to the emergency department complaining of lightheadedness and dizziness, particularly when standing up. His blood pressure is 90/60 mmHg, and his heart rate is 70 bpm. His electrolytes show a potassium level of 6.2 mmol/L. Which of the following is the most likely cause of his hyperkalemia?

A. Adrenal insufficiency
B. Gliclazide
C. Perindopril
D. Dehydration
E. Metformin
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the emergency department complaining of abdominal pain, distension, and obstipation for the past 3 days. He reports a history of multiple abdominal surgeries for adhesions. His vital signs are: HR 110 bpm, BP 110/70 mmHg, RR 22 breaths/min, SpO2 97% on room air, and temperature 37.8°C. Physical examination reveals a distended abdomen with high-pitched bowel sounds. An upright abdominal X-ray is performed, as shown. Given the clinical context and the findings on the imaging, what is the MOST appropriate next step in management?

A. Insert a nasogastric tube and initiate intravenous fluid resuscitation
B. Prescribe oral laxatives and encourage increased fluid intake
C. Administer intravenous antibiotics and schedule an urgent CT scan with oral contrast
D. Order a barium enema to assess for colonic obstruction
E. Perform a flexible sigmoidoscopy to rule out sigmoid volvulus
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 72-year-old male presents to the ED with sudden onset shortness of breath and right-sided chest pain. He has a history of atrial fibrillation and has been taking warfarin for the past 5 years. His INR is currently 6.0. A CT scan of the chest is performed (image attached). What is the MOST appropriate initial management step?

A. Administer intravenous vitamin K and prothrombin complex concentrate (PCC)
B. Administer intravenous tranexamic acid
C. Administer intravenous protamine sulfate
D. Perform a needle thoracostomy
E. Observe and monitor the patient's respiratory status
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Ovarian Cyst
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 62-year-old woman presents with a 4-month history of increasing abdominal distension, bloating, and a sensation of early fullness after eating. She has also noticed a gradual increase in her waist circumference and reports feeling more fatigued than usual. Her medical history includes well-controlled type 2 diabetes mellitus and hypercholesterolaemia, managed with metformin and atorvastatin respectively. She is post-menopausal, having completed menopause 10 years ago. On physical examination, her vital signs are stable: blood pressure 128/78 mmHg, heart rate 68 bpm, respiratory rate 14/min, and temperature 36.6°C. Abdominal examination reveals moderate distension and a firm, irregular mass is palpable extending from the pelvis into the lower abdomen. Bowel sounds are present and normal. A recent transvaginal ultrasound was inconclusive due to the size of the mass, prompting a CT scan of the abdomen and pelvis, an axial image from which is shown. Given the clinical presentation and the findings on the image, what is the most appropriate immediate next step in the management of this patient?

A. Arrange for a fine needle aspiration biopsy of the mass under CT guidance.
B. Prescribe a course of broad-spectrum antibiotics for presumed pelvic inflammatory disease.
C. Schedule a follow-up CT scan in 3 months to monitor for changes in the mass size and appearance.
D. Referral to a gynaecological oncologist and measurement of serum CA-125.
E. Referral to a general surgeon for urgent exploratory laparotomy.
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CT, ultrasonography, SPECT and scintigraphy of intra-thyroid parathyroid adenoma
Image by Mnahi Bin Saeedan, Ibtisam Musallam Aljohani, Ayman Omar Khushaim, Salwa Qasim Bukhari, Salahudin Tayeb Elnaas CC BY 4.0 · Source

A 62-year-old woman presents with fatigue, bone pain, and constipation. Laboratory investigations reveal serum calcium 3.1 mmol/L, parathyroid hormone 180 pg/mL, and elevated 24-hour urine calcium excretion. Imaging studies are performed for pre-operative localisation, the results of which are shown. Considering the clinical context and the findings demonstrated in the images, which surgical approach is MOST likely indicated for definitive management?

A. Targeted parathyroidectomy via hemithyroidectomy
B. Medical management with cinacalcet
C. Minimally invasive parathyroidectomy
D. Bilateral neck exploration
E. Observation with regular calcium monitoring
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A 60-year-old non-smoker has a calculated 5-year cardiovascular disease risk of 12%. Based on current Australian guidelines, what is the most appropriate initial management focus?

A. Annual risk reassessment without intervention
B. Lifestyle modification and shared decision-making regarding pharmacotherapy
C. Immediate initiation of high-intensity statin therapy
D. Referral for specialist cardiology review
E. Low-dose aspirin therapy for primary prevention
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 62-year-old man presents to his GP with a history of a bulge in his right groin that has been present for approximately 18 months. He reports it is more prominent with straining or standing and disappears completely when he lies down. He denies any associated pain, nausea, vomiting, or change in bowel habits. He has no significant past medical history. His physical examination reveals the finding depicted in the image. Vital signs are within normal limits. Based on this clinical picture, which of the following represents the most appropriate definitive management strategy for this patient?

A. Observation with regular follow-up.
B. Urgent surgical exploration.
C. Further imaging to confirm the diagnosis.
D. Elective surgical repair.
E. Non-surgical management with a supportive device.
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 65-year-old presents with 2 days of left lower quadrant pain, fever (38.5°C), and nausea. On examination, there is localised tenderness in the LLQ. Vitals: BP 130/80, HR 90, RR 16, SpO2 98%. CRP is 150 mg/L, WCC 18 x 10^9/L. This image is obtained as part of the workup. Based on the clinical presentation and imaging findings, what is the most appropriate initial management step?

A. Admission for intravenous antibiotics and observation.
B. Outpatient oral antibiotics and pain relief.
C. Elective colonoscopy in 6-8 weeks.
D. Percutaneous drainage of any fluid collection.
E. Urgent surgical consultation for laparotomy.
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 68-year-old male on warfarin presents with pleuritic chest pain and mild dyspnea. INR is 4.5. The image was obtained. What is the MOST appropriate initial intervention?

A. Observation and serial chest X-rays
B. Urgent bronchoscopy
C. Vitamin K administration
D. Chest tube insertion
E. IV protamine sulfate
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 72-year-old male presents to his general practitioner with a 3-month history of progressively worsening constipation alternating with episodes of loose stools, associated with occasional bright red blood per rectum and an unintentional weight loss of 4 kilograms over the same period. He denies any significant past medical history or family history of bowel disease. His vital signs are stable, and physical examination, including abdominal palpation and digital rectal examination, is unremarkable. Routine blood investigations reveal a haemoglobin of 105 g/L with a mean corpuscular volume of 78 fL, and normal inflammatory markers. Given the clinical presentation, a colonoscopy is performed. The image provided is a representative view obtained during this procedure. Based on the findings demonstrated in the image, what is the most appropriate immediate next step in the management of this patient?

A. Refer for urgent surgical resection without further investigation.
B. Obtain biopsies from the lesion and arrange for CT staging of the chest, abdomen, and pelvis.
C. Initiate a course of broad-spectrum antibiotics for presumed infectious colitis.
D. Schedule a repeat colonoscopy in 6 months to monitor the lesion's progression.
E. Prescribe a high-fibre diet and laxatives to manage the constipation.
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A 68-year-old man with hypertension presents with sudden onset right-sided weakness and slurred speech. GCS is 13. BP 190/110 mmHg. What is the most critical initial investigation to guide management?

A. CT angiography
B. Lumbar puncture
C. Non-contrast CT head
D. ECG
E. MRI brain
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 72-year-old male presents with a 4-month history of increasing fatigue, anorexia, and a 10 kg weight loss. He reports occasional nausea but no vomiting or abdominal pain. His vital signs are stable. Physical examination reveals mild jaundice and palpable hepatomegaly. Blood tests show Hb 105 g/L, elevated AST/ALT, and a mildly raised bilirubin. An upper endoscopy showed a large gastric mass, with histology pending. A CT scan of the abdomen and pelvis was performed. Considering the clinical context and the findings on the provided imaging, what is the most likely implication for this patient's overall management strategy?

A. Referral for liver transplantation assessment.
B. Planning for curative surgical resection of the primary tumour and liver lesions.
C. Urgent initiation of aggressive systemic chemotherapy with curative intent.
D. Focus on symptom control and quality of life measures.
E. Further investigation with MRI liver to characterise the lesions.
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents for a routine check-up. He has a history of smoking and hypertension, managed with lisinopril. He denies any abdominal pain, back pain, or lower extremity claudication. Physical exam is unremarkable. A contrast-enhanced CT scan of the abdomen is performed, the axial view is shown. What is the MOST appropriate next step in management?

A. Repeat imaging in 6-12 months
B. Start aspirin for secondary prevention
C. Refer to vascular surgery for elective repair
D. Prescribe a statin for lipid management
E. Initiate beta-blocker therapy
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 75-year-old female presents to the emergency department with a 24-hour history of worsening colicky abdominal pain, nausea, and multiple episodes of bilious vomiting. She reports no passage of flatus or stool for the past 18 hours. Her past medical history includes an open appendectomy 30 years ago and a hysterectomy 10 years ago. On examination, she is afebrile, heart rate 92 bpm, blood pressure 130/80 mmHg, respiratory rate 18/min, oxygen saturation 98% on room air. Her abdomen is distended and diffusely tender to palpation, with high-pitched tinkling bowel sounds on auscultation. A plain abdominal X-ray series, including the image provided, was obtained. Considering the patient's clinical presentation and the findings demonstrated in the provided image, which of the following represents the most appropriate immediate next step in her management?

A. Administer a large volume enema
B. Administer broad-spectrum intravenous antibiotics
C. Order a CT scan of the abdomen and pelvis with intravenous contrast
D. Proceed directly to exploratory laparotomy
E. Insert a nasogastric tube for decompression
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 72-year-old male with a history of atrial fibrillation and well-controlled hypertension presents with acute onset expressive aphasia and right-sided facial droop. A CT angiogram reveals a posterior cerebral artery aneurysm, which was promptly treated with endovascular coiling. The provided image shows the post-operative angiogram. Despite the intervention, the patient's aphasia persists, and the facial droop has worsened. What is the MOST likely cause of the patient's continued and worsening symptoms?

A. Intracranial pressure elevation due to edema
B. Reperfusion injury following aneurysm coiling
C. Underlying progressive neurodegenerative disease
D. Thromboembolic complication during the coiling procedure
E. Vasospasm of the posterior cerebral artery
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 65-year-old male presents with left lower quadrant abdominal pain for 3 days, associated with constipation. He denies fever. An abdominal CT scan is performed, the axial view is shown. What dietary advice is MOST appropriate at discharge?

A. Strictly liquid diet for 2 weeks
B. Low-residue diet until symptoms resolve
C. High-fiber diet with adequate fluid intake
D. Gluten-free diet
E. Avoidance of nuts and seeds
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 72-year-old woman presents with increasing pain in her right leg. She has been on warfarin for atrial fibrillation for the past 5 days. Her INR is currently 3.5. Examination reveals the findings shown. What is the MOST appropriate next step in management?

A. Prescribe oral antibiotics
B. Apply topical corticosteroids
C. Stop warfarin and administer vitamin K
D. Continue warfarin at the same dose
E. Start intravenous heparin
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 68-year-old man with known alcoholic cirrhosis presents for routine surveillance. He reports mild fatigue. Liver function tests are within his baseline (Child-Pugh A). Alpha-fetoprotein is 150 ng/mL. The provided images are obtained. Considering the clinical context and the findings demonstrated in the images, which of the following treatment modalities is most likely to be considered first for this patient?

A. Transarterial chemoembolisation (TACE)
B. Surgical resection
C. Palliative care
D. Systemic targeted therapy (e.g., Sorafenib)
E. Liver transplantation assessment
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 78-year-old male presents to the emergency department with a 2-day history of intermittent upper abdominal pain radiating to the chest and mild dysphagia. He denies shortness of breath or fever. Vital signs are stable. A chest X-ray is obtained. Considering the radiographic findings in the context of the patient's presentation, what is the most appropriate immediate management plan?

A. Admit for observation and serial cardiac enzymes.
B. Perform a bedside echocardiogram to assess cardiac function.
C. Order a contrast-enhanced CT scan of the abdomen and pelvis.
D. Referral for urgent surgical consultation.
E. Initiate high-dose proton pump inhibitor therapy and arrange outpatient follow-up.
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A 70-year-old woman with a history of hypertension presents with fatigue, shortness of breath, and bilateral leg swelling. Echocardiography shows an ejection fraction of 30%. What is the most appropriate first-line treatment?

A. Calcium channel blocker
B. Nitrate therapy
C. ACE inhibitor and beta-blocker
D. Digoxin
E. Diuretic therapy alone
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A 70-year-old man with severe COPD (FEV1 35%) presents with increased cough, purulent sputum, and dyspnoea over 48 hours. He uses salbutamol PRN and tiotropium daily. His oxygen saturation is 88% on room air. Chest X-ray shows hyperinflation but no new consolidation. What is the most appropriate initial management step?

A. Administer controlled oxygen therapy targeting SpO2 88-92%.
B. Perform arterial blood gas analysis.
C. Initiate intravenous antibiotics.
D. Prescribe high-dose inhaled corticosteroids.
E. Administer nebulised salbutamol and ipratropium bromide.
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 72-year-old patient presents with intermittent chest discomfort and increasing shortness of breath, particularly after meals. Vitals are stable. Physical examination is unremarkable. A chest X-ray is performed. Considering the radiographic findings in the context of the patient's symptoms, what is the most appropriate next step in management?

A. Trial of high-dose proton pump inhibitors
B. High-resolution CT chest
C. Barium swallow study
D. Referral for surgical assessment and repair
E. Urgent cardiac catheterisation
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

An 82-year-old patient presents to their GP with a 3-month history of intermittent retrosternal chest discomfort, often described as a burning sensation, worse after meals and when lying flat. They also report mild shortness of breath on exertion and occasional regurgitation, but deny significant dysphagia or weight loss. Past medical history includes hypertension and osteoarthritis. Medications are perindopril and paracetamol. On examination, vital signs are stable (BP 130/80, HR 75, RR 16, SpO2 97% on air), and lung sounds are clear. A chest X-ray is performed as part of the workup. Based on the clinical context and the findings demonstrated in the image, what is the most appropriate next step in investigation?

A. Reassure the patient that the X-ray is normal and advise lifestyle modifications
B. Oesophago-gastro-duodenoscopy (OGD)
C. Refer for formal cardiac stress testing
D. Commence a trial of high-dose proton pump inhibitor (PPI) therapy
E. Perform pulmonary function tests (PFTs)
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A 72-year-old man with a history of hypertension and type 2 diabetes mellitus is being managed with lisinopril. He presents to the emergency department complaining of lip swelling and difficulty breathing. On examination, his tongue appears swollen. What is the most appropriate immediate management?

A. Administer intramuscular epinephrine
B. Administer intravenous corticosteroids
C. Administer nebulized bronchodilators
D. Administer intravenous antihistamines
E. Observe and monitor vital signs
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

An 82-year-old woman with a history of paroxysmal atrial fibrillation was recently discharged from hospital following treatment for community-acquired pneumonia. Five days ago, she was commenced on warfarin 5mg daily for stroke prevention. She presents to the emergency department today complaining of severe, rapidly worsening pain and a dark, blistering lesion on her right lower leg that developed over the past 48 hours. She denies any recent trauma to the leg. Her vital signs are stable: blood pressure 132/82 mmHg, heart rate 76 bpm, respiratory rate 18/min, temperature 37.0°C. Physical examination reveals the appearance shown in the image on her right anterior lower leg. Laboratory results show an INR of 4.8, haemoglobin 125 g/L, white cell count 8.5 x 10^9/L, and platelets 250 x 10^9/L. She has no known personal or family history of thrombophilia. Considering the clinical presentation, recent medication changes, and the appearance depicted, which of the following is the most appropriate immediate management strategy?

A. Discontinue warfarin, administer Vitamin K, and initiate therapeutic dose low molecular weight heparin.
B. Reduce the dose of warfarin and monitor the INR closely.
C. Discontinue warfarin and administer Vitamin K only.
D. Initiate broad-spectrum intravenous antibiotics and arrange urgent surgical review for debridement.
E. Continue warfarin at the current dose and administer fresh frozen plasma to correct the INR.
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 62-year-old woman presents for a routine follow-up appointment several years after undergoing a simple mastectomy for pT1N0M0 invasive ductal carcinoma of the left breast. She completed adjuvant endocrine therapy and has been well since, reporting no new systemic symptoms such as unexplained weight loss, fatigue, or bone pain. Her last mammogram of the contralateral breast and clinical examination at her previous visit six months ago were unremarkable. During the current consultation, she mentions that she has noticed a persistent area of skin change on her left chest wall, near the mastectomy scar, over the past few months. She describes it as occasionally itchy and slightly raised, but denies pain, discharge, or significant discomfort. Her vital signs are stable (BP 130/80 mmHg, HR 72 bpm, RR 16/min, Temp 36.8°C). Physical examination reveals no palpable axillary or supraclavicular lymphadenopathy. The appearance of the affected area is shown in the image. Considering the patient's history, the duration and nature of the symptoms, and the clinical presentation, what is the most appropriate initial diagnostic step to investigate this new finding?

A. Prescribe a course of topical antifungal cream and review in two weeks.
B. Perform a punch biopsy of the affected skin area.
C. Arrange for a repeat mammogram of the contralateral breast and ultrasound of the axilla.
D. Order a CT scan of the chest, abdomen, and pelvis to rule out metastatic disease.
E. Reassure the patient that this is likely a benign inflammatory reaction related to the scar and monitor clinically.
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A 68-year-old man with moderate COPD (FEV1 55%) on a LAMA reports persistent breathlessness (mMRC 2) and one moderate exacerbation requiring oral steroids last year. What is the most appropriate next step in maintenance therapy?

A. Add an inhaled corticosteroid (ICS).
B. Increase the dose of the current LAMA.
C. Switch LAMA to a long-acting beta-agonist (LABA).
D. Add a short-acting beta-agonist (SABA) as regular therapy.
E. Add a long-acting beta-agonist (LABA).
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 65-year-old male presents with a 2-month history of fatigue, poor appetite, and 5kg weight loss. He reports mild upper abdominal discomfort. Physical examination is unremarkable. Initial blood tests show mild anaemia. An upper endoscopy revealed a suspicious gastric lesion, with biopsy results pending. A CT scan of the abdomen and pelvis was performed. Given the clinical presentation and the findings on the provided imaging, which of the following statements regarding this patient's likely prognosis and management is most accurate?

A. The extensive nature of the findings suggests limited options for curative treatment, with systemic therapy typically employed for palliation or disease control.
B. A watch-and-wait approach with repeat imaging in 3-6 months is recommended.
C. Referral for surgical assessment for potential hepatectomy is the next appropriate step.
D. Liver-directed therapies such as transarterial chemoembolisation (TACE) should be pursued.
E. The findings are likely benign and require no further intervention beyond managing the primary gastric lesion.
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CT, ultrasonography, SPECT and scintigraphy of intra-thyroid parathyroid adenoma
Image by Mnahi Bin Saeedan, Ibtisam Musallam Aljohani, Ayman Omar Khushaim, Salwa Qasim Bukhari, Salahudin Tayeb Elnaas CC BY 4.0 · Source

A 62-year-old woman presents to her general practitioner complaining of fatigue, bone pain, and constipation for the past several months. She denies any significant past medical history and her vital signs are stable. Initial laboratory investigations reveal an elevated serum calcium level of 3.1 mmol/L (reference range: 2.1-2.6 mmol/L) and an elevated parathyroid hormone (PTH) level of 180 pg/mL (reference range: 10-65 pg/mL). A 24-hour urine calcium excretion is also elevated. The patient is referred for further imaging, the results of which are shown. Based on the available information, what is the MOST appropriate next step in the management of this patient?

A. Referral for surgical parathyroidectomy
B. Order a DEXA scan to assess bone mineral density
C. Initiate medical management with cinacalcet
D. Repeat parathyroid hormone and calcium levels in 3 months
E. Prescribe bisphosphonates to reduce bone resorption
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents to the ED with left lower quadrant abdominal pain, fever, and leukocytosis. A CT scan of the abdomen and pelvis is performed. Based on the imaging, what is the MOST appropriate next step in management?

A. IV antibiotics and bowel rest
B. Surgical resection of the affected bowel segment
C. Flexible sigmoidoscopy to rule out malignancy
D. Increase dietary fiber intake and follow up with GP
E. Stool culture to rule out infectious colitis
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 72-year-old woman presents with a 6-month history of a non-healing rash on her chest wall at the site of a previous mastectomy performed 10 years prior for invasive ductal carcinoma. She has completed adjuvant chemotherapy and radiation. Examination reveals the findings shown. What is the MOST appropriate next step in management?

A. Skin biopsy of the affected area
B. Topical corticosteroid application
C. Referral for wide local excision
D. Empiric antibiotic therapy
E. Fungal culture of the lesion
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 72-year-old woman on warfarin for chronic atrial fibrillation presents with a painful, rapidly expanding lesion on her right lower leg that began two days ago, shortly after her warfarin dose was increased. Her vital signs are stable, and her INR is within the therapeutic range. Considering the clinical presentation and the appearance of the lesion shown, what is the most appropriate immediate management?

A. Administer broad-spectrum antibiotics and arrange urgent surgical debridement.
B. Switch warfarin to a direct oral anticoagulant (DOAC).
C. Discontinue warfarin, administer vitamin K, and initiate heparin.
D. Continue warfarin at the current dose and monitor closely.
E. Reduce the warfarin dose and add aspirin.
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 68-year-old man presents to his GP with a 4-month history of increasing constipation alternating with loose stools, occasional rectal bleeding, and a feeling of incomplete evacuation. He reports fatigue but denies significant weight loss. His physical examination, including digital rectal examination, is normal. Full blood count shows a haemoglobin of 115 g/L with low ferritin. A colonoscopy is performed, and the image provided is a representative view from the procedure. Considering the clinical presentation and the finding observed during the colonoscopy, what is the most appropriate immediate next step in the management of this patient?

A. Obtain biopsies from the lesion for histological assessment and arrange for staging investigations.
B. Schedule a repeat colonoscopy in 6 months to assess for changes in the appearance of the lesion.
C. Prescribe a course of oral corticosteroids for presumed inflammatory bowel disease.
D. Recommend dietary modification and bulk-forming laxatives to manage the change in bowel habit.
E. Refer the patient directly for urgent surgical consultation and resection planning.
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A 70-year-old woman with a history of hypertension and chronic kidney disease (CKD) stage 3 is prescribed an ACE inhibitor for blood pressure control. Which of the following parameters requires the closest monitoring after initiating the ACE inhibitor?

A. Liver function tests
B. Thyroid stimulating hormone (TSH)
C. Serum creatinine and potassium
D. Serum calcium
E. Complete blood count
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A 66-year-old man, active with a good diet, whose mother had osteoporosis at age 91, wants to check his osteoporosis risk. What risk factors prompt a bone mineral density (BMD) test?

A. Asthma
B. Rheumatoid arthritis
C. Generalized anxiety disorder
D. Type 2 Diabetes Mellitus
E. Hypertension
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